Image: Sniffer
dogs detecting the presence of infection in a sample Credit:
Medical Detection Dogs
|
Pilot studies have shown that
distinctive chemicals are found in the breath of people infected with malaria
and dogs could be trained to identify these
Distinctive chemicals found in the breath of people
infected with malaria can
be sniffed out by dogs, according to new research.
The project, led by scientists from the London
School of Hygiene and Tropical Medicine, has been awarded a £70,000 grant by
The Bill and Melinda Gates Foundation to further the research. It is also being
supported by the University of Durham, the Medical Research Council (MRC) in
Gambia and UK charity Medical Detection Dogs.
Dogs and
their acute sense of smell can already track down drugs, pursue suspects and
find dead bodies – and malaria could soon be added to that list.
To conduct the research, James Logan, senior
lecturer in Medical Entomology at the London School and his team will work with
the MRC Unit in Gambia to collect urine and sweat samples from 400 Gambian
children, including a number who are known to have malaria.
The children will be asked to wear nylon socks
for 24 hours, which will be used together with skin swabs to provide sweat
samples. The dogs will then be trained to distinguish between positive and
negative samples using odour clues.
Tests for malaria currently involve taking blood
samples by pricking the fingers of patients. These samples are then screened in
a lab. A non-invasive method that doesn't require blood samples and technical
expertise could therefore improve the detection rate.
"Dog detectives do not require a laboratory;
they are portable, inexpensive, and could rapidly screen many
individuals," wrote Logan in a blog post.
"They could be particularly useful in
detecting malaria in communities where only a few people carry the parasite,
since identifying these people, who are acting as 'reservoirs' that maintain
malaria in the population, would allow us to eradicate the disease far more
rapidly."
"In addition, once areas are malaria-free,
dogs could be used at entrances to villages, communities and even countries to
detect and treat people carrying the disease before entering."
Last
year there were 214 million malaria cases and an estimated 438,000 deaths
Credit: iStock/Manjurul
|
Sniffer dogs and disease
The malaria project isn't the first time dogs
have been used in health-related trials.
Last year, a German Shepherd called Frankie was
trained to sniff out thyroid cancer in urine samples with a success rate of 88
per cent. He was trained at the University of Arkansas for Medical Sciences,
and the team hailed Frankie for his "unbelievable" sense of smell.
"This is a fascinating, interesting
study" said endocrinologist Dr Jason Wexler at the time. "It has high
potential in areas of the world which may not have access to biopsy
techniques."
It followed a 2014 trial with Daisy the Labrador in which the dog could sniff out breast cancer in 550 samples of breath, skin
and urine.
No comments :
Post a Comment